It is the Taisho Period (i.e. 1912-1926). Tanjiro Kamado is living a modest but blissful life in the mountains with his family. One day, when he returns from selling charcoal in town, he finds the remains of his slaughtered family in pools of blood after a demon attack. Tanjiro rushes down the snowy mountain with the sole survivor, his sister Nezuko, on his back. But on the way, Nezuko suddenly snarls, turning on Tanjiro.

Now split into three, the demons have driven Tanjiro into a corner. It is then that Nezuko attacks. Now that she’s become a demon herself, she’s no longer so weak that she needs protection. His mind made up, Tanjiro follows one of the demons into the swamp now spreading across the ground. Waiting for him there is...

The next mission is in Asakusa, Tokyo. Tanjiro is taken aback by the opulent Taisho Era cityscape, but soon picks up the demon’s scent there. His pursuit of the scent leads him to Muzan Kibutsuji. Tanjiro attempts to strike him down. But Kibutsuji transforms a passerby into demon, triggering a commotion. As Tanjiro desperately tries to get things under control, someone appears before him...

Tanjiro's next destination, according to his Kasugai Crow, is to the south-southeast. On the way, Tanjiro runs into his fellow Final Selection survivor, the swordsman Zenitsu Agatsuma. Tanjiro has a hard time dealing with Zenitsu's passive attitude as they head deep into the mountains. They encounter two children whose older brother was taken away right in front of their house. There, Zenitsu hears the sound of a tsuzumi ringing out from somewhere.

When Rui assaults him with his Blood Demon Art, Tanjiro braces himself for certain death. As his life flashes before his eyes, he suddenly remembers his father's dance, the kagura, and unleashes a new, non-Water Breathing attack. Hinokami Kagura Dance. Knowing that he’ll be receiving a simultaneous blow from the demon, he uses his new move to slice off Rui’s head. As Tanjiro crawls towards Nezuko, who lies on the ground, riddled with wounds, someone appears before him.

An Upper Rank Demon has been defeated for the first time in a hundred years by Uzui, Tanjiro, and his comrades' effort. This news causes a ripple effect not only among the members of the Demon Slayer Corps, but also the Upper Rank Demons, who have been summoned by Muzan Kibutsuji. Meanwhile, Tanjiro is recovering at the Butterfly Mansion when he discovers that he has upset his swordsmith Haganezuka after chipping his sword and decides to head to the village where the swordsmiths live to talk to him in person.

Tanjiro continues the fight against Hantengu. Amidst all his injuries and the Superior Four's skill, will he be able to defeat him? As the battle draws to a close, the Demon Slayer Squad must race against time to end the fight before dawn.