Yuri is in town all dressed up for a date when a dying agent from the 3WA (World, Welfare, and Works Agency) hands her a special card to give to headquarters. Yuri is reluctant to take it until some guys in blue uniforms arrive and chase her down. She passes the card to her reluctant partner Kei, but somehow the blue uniform guys grab it. Kei and Yuri go after the guys, but also have to evade them when the girls secure the card, and they end up having to go through some bad sections of town, leaving a wake of destruction along the way.

After spotting bigwig Waldess at his GCN corporation, Kei tries to confront him but the bodyguards apprehend her and toss her out. Frustrated, Kei has had enough, and resigns. Yuri is assigned to protect a neuroscientist, but runs into trouble as Lady Flair storms in to kill the scientist. Waldess takes a sabbatical to a cruiser ship on a planet's ocean full of deadly whirlpools. Kei pursues her but gets into trouble as Lady Flair is aboard the ship, and Yuri pursues to try to help out.

With Kaps's testimony, the GCN is being investigated. The guys that represent Lucifer decide that Waldess is too dangerous especially when he's still going after Siren, so they hire an assassin, who is none other than Lady Flair! Kei gets her gun repaired but it got confiscated by the 3WA. Meanwhile, Yuri gets a new ditzy partner named Lilly, and they have to help Unit 9 stake out Waldess at a spaceport, but trouble arises when other assassins make their moves against Waldess.

The rain catches Yuri and Touma in the city and they end up at a flower shop where Touma falls in love with a girl who works there. Kei and Yuri pick up on the computer geek's change in mood, and readily give him love advice on the scary thought of asking the girl out.

Kei is on a plane trip but some enemy fighter plane is after them and it shoots the plane down into the snow covered mountains. Kei manages to save a baby as she bails out in time before the big crash and explosion, but not only does she have to deal with calming down a baby, but also the bad guys who pursue them with intent to kill.

A teenage girl named Monica has been training all her life to carry on her family's deadly assassin heritage. Her first assignment is to go after the Dirty Pair. Kei and Yuri go to a vacation resort to relax but soon find themselves on the guard as bombs, traps, and deadly attacks appear wherever they go.

A felon sprung out of prison transport makes a deal with a crime boss to command and pilot an advanced assault mech, but first he wants to borrow the mech to go after Chief Poporo of the 3WA. Soon afterwards, bombs start going off all over the city and the Chief's life is in danger as the mech raids 3WA Headquarters. Kei and Yuri try to protect him, but what complicates things even more is that the Chief's daughter is at the office for a visit.