The fate of the galaxy rests in the hands of bitter rivals. One, James Kirk, is a delinquent, thrill-seeking Iowa farm boy. The other, Spock, a Vulcan, was raised in a logic-based society that rejects all emotion. As fiery instinct clashes with calm reason, their unlikely but powerful partnership is the only thing capable of leading their crew through unimaginable danger, boldly going where no one has gone before. The human adventure has begun again.

En route to the honeymoon of William Riker to Deanna Troi on her home planet of Betazed, Captain Jean-Luc Picard and the crew of the U.S.S. Enterprise receives word from Starfleet that a coup has resulted in the installation of a new Romulan political leader, Shinzon, who claims to seek peace with the human-backed United Federation of Planets. Once in enemy territory, the captain and his crew make a startling discovery: Shinzon is human, a slave from the Romulan sister planet of Remus, and has a secret, shocking relationship to Picard himself.

The crew of the Federation starship Enterprise is called to Nimbus III, the Planet of Intergalactic Peace. They are to negotiate in a case of kidnapping only to find out that the kidnapper is a relative of Spock. This man is possessed by his life long search for the planet Sha Ka Ree which is supposed to be the source of all life. Together they begin to search for this mysterious planet.