On an ocean liner crossing a professional gambler comes to the aid of a naive young man victimized by a jewel thief. The young man turns out to be his son he's not seen since infancy.
No one thought Donna would go very far. But when she sets her sights on becoming a first-class international flight attendant, Donna throws caution to the wind and takes off in pursuit of her dream. The ride is anything but smooth, however, and Donna's laugh-packed journey of a lifetime is rocked by more turbulence than she bargained for.
FBI agent Neville Flynn boards a flight from Honolulu, Hawaii to Los Angeles, escorting a key witness to testify against a mob boss at an upcoming trial. An on-board assassin releases a crate full of hundreds of deadly venomous snakes in an attempt to eliminate the witness. Flynn and a host of frightened passengers and crew must band together to survive the slithery threat.