After a band of drunken thugs overruns a small Indian Nation town, killing Reverend Goodnight and raping the women folk, Eula Goodnight enlists the aid of US Marshal Cogburn to hunt them down and bring her father's killers to justice.

Dusty Gardner, and other Texas ranchers, are driving a herd of cattle to Abilene, Kansas along the Chisholm Trail. Desperate need of water takes them to the Turner ranch, where Belle Turner demands exorbitant prices for the water. Dusty learns that Belle is also trying to oust Mary Lee and Montana Smith from the trading post Mary operates. The sheriff sides with Belle following a fight between the two women. Belle knows there is artesian springs under the land the trading post occupies and intends to get the property by any means.

When a cold medicine causes Sach to be able to smell diamonds, he and the rest of the Bowery Boys are induced by a diamond dealer to accompany him to Darkest Africa in search of a legendary cache of them.

John Meadham, in charge of a West Africa trading post, wire the home office in London that he is tired and worn out, and they need to send a replacement to take over. The company sends a stiff upper-lipper, Charles Summers, accompanied by his wife, Margaret. An antagonism develops between the two men from the moment Summers arrives.

Prospector Jeff Malloy rescues Doris Devlin, owner of a trading post, from an ambush planned by her uncle, Kilburn, who is trying to scare her out of the territory so that he can continue his counterfeiting operations.

Canadian Mounties Corporal Rod Webb and Constable Mike Kelly, along with Rod's dog Chinook, are sent to the Blackfoot Crossing country to find a killer.