The son of a notorious serial killer becomes an acclaimed criminal psychologist who uses his unique insight into how killers think to help the NYPD.
Cassie Bedford has visions... whether she likes it or not. Sometimes she encounters unsettled spirits who need her help. When her father, Detective Tom Hackett, and his new partner, former FBI agent Damien Asante, need assistance, Cassie reluctantly uses her abilities and helps solve some of the city’s most challenging cases.
Erica Shepherd is a brilliant former CIA operative, now known as the most notorious traitor in American history serving life in a Supermax prison. Against every fiber of his being but with nowhere else to turn, FBI Agent Will Keaton enlists Shepherd to help track down a fiercely dangerous and elusive criminal she knows all too well. While Shepherd and Keaton have different motivations for bringing the enemy to justice, they both know that to catch a spy… they must think like one.
Dr. Dylan Reinhart, a gifted author, university professor and former CIA operative is lured back to his old life by tenacious top NYPD Detective Lizzie Needham. Though Dylan and Lizzie initially clash, when it comes to catching killers, they make an ideal team.
Cameron Black is the world's greatest illusionist. At least, that's what people used to call him—before his greatest secret was exposed and his career destroyed. Even worse, Cameron has good reason to believe this was no accident.
A tech innovator creates a cutting-edge crowd-sourcing hub to solve his own daughter's murder, as well as revolutionizing crime solving in San Francisco.
Jasper Teerlinck, an eccentric professor, is an adviser to the police.
Felix Winterberg is the great-great-grandson of the famous Albert Einstein and himself a recognized physics genius. Because of a deadly hereditary disease, the brilliant researcher only has a few years left - which he wants to make as labor-intensive as possible thanks to various illegal stimulants.
The Nantes Homicide Department has saddled itself with a team of high-powered experts who are aces in solving murders yet cannot carry on a normal conversation. Criminologist Julien Tardieu has a brilliant mind and a few – dozen? – neurological disorders. This Sherlock needs two Watsons: Inspectors Lise Doumère is the volcanic, explosive one and Dan Levasseur is the quiet behind-the-scenes operator.
Raymond "Red" Reddington, one of the FBI's most wanted fugitives, surrenders in person at FBI Headquarters in Washington, D.C. He claims that he and the FBI have the same interests: bringing down dangerous criminals and terrorists. In the last two decades, he's made a list of criminals and terrorists that matter the most but the FBI cannot find because it does not know they exist. Reddington calls this "The Blacklist". Reddington will co-operate, but insists that he will speak only to Elizabeth Keen, a rookie FBI profiler.
Both a gift and a curse, Graham has the extraordinary ability to think like his prey—he sees what they see, feels what they feel. But while Graham is pursuing an especially troubling, cannibalistic murderer, Special Agent Jack Crawford teams him with a highly respected psychiatrist – a man with a taste for the criminal minded – Dr. Hannibal Lecter.
Dr. Daniel Pierce, a neuroscientist and professor, is recruited to help the federal government crack difficult cases. His intimate knowledge of human behavior and masterful understanding of the mind give him an extraordinary ability to read people, but his eccentric view of the world and less-than-stellar social skills can often interfere with his work.
Driven by the fact that there are few things more dangerous than a prisoner who has just escaped, and tired of following protocol and resorting to outdated methods of law enforcement, veteran U.S. Marshals Charlie Duchamp and Ray Zancanelli are taking an unorthodox approach to their work: using former fugitives to catch fugitives.
In exchange for his freedom, charming con artist Neal Caffrey provides his expertise to help straight-man FBI agent Peter Burke catch elusive white-collar criminals.
Toby Logan is a highly skilled paramedic with a secret – he can read minds. Toby never really knew his parents and grew up in foster care, this coupled with his secret, which he shares with no one, has made him a bit of a loner. Until now, Toby has kept his ability hidden, exploring its possibilities only with his long time mentor and confidante Dr. Ray Mercer.
After a serial killer imitates the plots of his novels, successful mystery novelist Richard "Rick" Castle receives permission from the Mayor of New York City to tag along with an NYPD homicide investigation team for research purposes.
The world's leading deception researcher, Dr. Cal Lightman, studies facial expression, body language and tone of voice to determine when a person is lying and why, which helps law enforcement and government agencies uncover the truth. But his skills also make it easier for him to deceive others.
Dr. Jacob Hood is a brilliant biophysicist and special science advisor to the government who investigates scientific crises and oddities. His crusade is to protect the substance of science against those who would abuse and misuse scientific discoveries for their own gain.
Patrick Jane, a former celebrity psychic medium, uses his razor sharp skills of observation and expertise at "reading" people to solve serious crimes with the California Bureau of Investigation.