A young idealistic doctor works at his father's clinic in a small and seedy district. During the war, he contracts syphilis from the blood of a patient when he cuts himself during an operation. Treating himself in secret and tormented by his conscience, he rejects his heartbroken fiancée without explanation.

During the start of the Pacific campaign in World War II, Lieutenant Janet Davidson is the head of a group of U.S. military nurses who are trapped behind enemy lines in the Philippines. Davidson tries to keep up the spirits of her staff, which includes Lieutenants Joan O'Doul and Olivia D'Arcy. They all seek to maintain a sense of normal life, including dating, while under constant danger as they tend to wounded soldiers.

The Army nurses on Bataan need help badly, but when it arrives, it sure isn't what they expected. A motley crew, including a Southern belle, a waitress, and a stripper, show up. Many conflicts arise among these women who are thrown together in what is a desperate and ultimately hopeless situation.

Untrained, volunteer Nurses from America treat Allied soldiers behind and on the lines in France. They face the horrors of war, fight off the attentions of soldiers and face their own loneliness.

With no other prospects, a World War I veteran puts the skills they taught him in the War to use.