Candy, a fairy from Märchenland follows the shining light that leads to the five legendary PreCure warriors in order to fight Bad End Kingdom villains who are trying to vanquish the entire world to the “Worst Ending.

In Animal Town where humans and animals live together, Iroha who loves animals is very close to her dog Komugi! One day, a mysterious creature called a GaruGaru goes berserk in her city. In order to protect Iroha, Komugi transforms into a human and even a Pretty Cure…!? We have to protect such berserk animals! Let's join forces and return the animals to the Niko Garden!

Manatsu Natsuumi is a first-year junior high school student born and raised on a small island. On the day she moves from the island, She meets Laura, a mermaid girl who has come to the earth alone in search of the legendary warrior, PreCure. Laura's hometown, Grand Ocean, is attacked by a witch who lives in the dark depths of the ocean, and all of their motivational power is taken away. It is said that if the motivational power of humans is also taken away, the world will be in deep trouble. Laura is captured by the witch's servant, and Manatsu transforms into Cure Summer to save her.

Ichika Usami is a second year middle school student whose family runs the Kirakira Patisserie shop. One day, she encounters a fairy named Pekorin and learns that evil monsters known as Henteko have been stealing "Kirakiraru", the energy that resides within sweets and desserts. Thus, Ichika becomes a Pretty Cure and, alongside four other cures, forms the Kirakira PreCure a la Mode to fight off the Henteko and protect the sweets.