Walter White, professeur de chimie dans un lycée d'Albuquerque au Nouveau-Mexique, est atteint d'un cancer pulmonaire en phase terminale. Il s'associe à Jesse Pinkman, un ancien élève, cancre, toxicomane et dealer, afin d'assurer l'avenir financier de sa famille après son décès. L'improbable duo va alors synthétiser et commercialiser la plus pure méthamphétamine en cristaux jamais vue dans les Amériques.
20-year-old Janine Grabowski disappears in a small Bavarian town near the Czech border. While all evidence indicates that Janine secretly wanted to leave the backcountry, her mother, Michelle, becomes increasingly convinced that there's something amiss. Michelle's missing person's report is quickly filed away by the police. So the single mother is forced to investigate at her own risk. The longer she hunts for an answer to Janine's disappearance, the more she discovers about her daughter and the people with whom she kept company. She begins to doubt whether Janine even wants to be found.