The Sakuragoaka Girls' Academy curriculum traditionally focuses on the three "R"s of reading, writing and arithmetic, but Ritsu Tainaka wants to add two more "R"s: Rock and Roll! To do that, however, Ritsu has to save the Light Music Club from being shut down due to little problems like not having any other members or a faculty advisor. After strong-arming her best friend Mio into joining and convincing Tsumugi Kotobuki to make it a trio, Ritsu's would-be rockers are soon only one talented guitarist short of the quartet they need for school approval. What they get, unfortunately, is Yui Hirasawa, who's never held a guitar in her life, but she's determined to learn! Will the school halls come alive with the sound of music?

Eriko and her friends Yuma and Ayano are excited about entering high school. Their excitement leads to their breaking of the rules when they toured the school before the opening ceremony. They find out their preconceptions about the all female school may not be as true as they had first thought. Despite that, Eriko and her friends are joined by new friends. They aim to get through high school life together.

When an apocalyptic tidal wave hits during the ten-year reunion of an all-girls high school, a group of women must find a way to survive on the island peak of their high school campus.