Christmas Eve, and Sniffles is determined to stay awake to see Santa. Not an easy task.

Sniffles the mouse and his friend the Bookworm try to evade a cat in a the toy department of Lacy's department store.

Sniffles the mouse's non-stop talking foils both the burglar and a tipsy Officer Bear, who's trying to sneak past his rolling pin-toting, sleepwalking wife.

A mouse adopts a hawk.

When his car breaks down out in the country, Sniffles the mouse takes shelter in an old mill, where he meets up with "Batty," a non-stop-talking little bat who later save Sniffles from a hungry cat.

Take-off on the "Duffy's Tavern" radio program, with tough-guy Eddie G. Robincat demanding a meal of mouse knuckles, "of which we ain't got none," waiter Filligan informs his absentee boss on the phone. To fill the plate, Filligan then tries to catch the blabbermouth mouse, Sniffles.

Sniffles the mouse's friends talk him into putting a bell around the neck of the troublesome house cat.