A rogue scientist near a small desert town arouses the suspicion of the town's doctor when his lab assistant is found dead from a case of acromegaly, which took only four days to develop. As the doctor investigates, aided by the scientist's new female assistant, they discover that something is devouring local cattle and humans in increasingly large quantities.

When Holly’s dark secret is accidentally uncovered by her new emotionally unstable neighbor Tom, they are pulled into a violent confrontation with her father, who will do anything to keep the secret hidden.

This doc investigates the odd occurrences that have happened for decades at a creek in Texas, which was an Ancient Native American burial ground.