曾经意气风发的高志垒（徐峥 饰）在生活的重压下，中年“失速”偏离了原本的生活轨迹，一时意气用事的决定，让他瞬间从家人的“小骄傲”变成了社会的“边角料”。然而，他未曾料到，这仅是他“逆行人生”道路上的起点。接连不断的变故如疾风骤雨般袭来，迫使他不得不重新面对自我。当生活的 重担真正压肩，他选择成为一名外卖员，从新的起点重新出发，穿梭于都市大街小巷的高志垒在路上结识了一众志同道合的“骑士”伙伴，在共度的时光里他深切的体会到了人间的冷暖真情，逐渐在这条充满磨砺的“逆 行道”中找回曾经丢失的勇气与信念，重新定义人生新的方向。

　　本片根据清明原著《逆行人生》改编。

Under the heavy pressure of life, Gao Zhilei (played by Xu Zheng), who was once full of energy, lost his speed and deviated from his original life trajectory in middle age. His impulsive decision instantly transformed him from a family's "little pride" into a "corner of society". However, he did not expect that this was only the starting point on his path of "reverse life". The continuous changes came like a storm, forcing him to face himself again. When the burden of life truly weighed down his shoulders, he chose to become a delivery man, starting from a new starting point and shuttling through the streets and alleys of the city, Gao Zhilei met a group of like-minded "knights" on the road. During the time spent together, he deeply experienced the warmth and coldness of the world, and gradually regained the courage and beliefs he had lost in this challenging "retrograde path", redefining a new direction in life.