Lovers Beatrice Dalle and Wadeck Stanczak can't quite cope with the situation when Dalle becomes pregnant. Stanczak fears that his future as an architect will be scuttled by any parental responsibilities. For her part, Dalle wants to keep the baby, but she also wants to keep Stanczak. Attempting to smooth the waters is the couple's mutual friend Francis Frappat. Chimere was the second feature-film project for director Claire Devers, who rose to prominence on the strength of her award-winning maiden effort Black and White.

Depuis qu'Alice est enceinte, le couple qu'elle forme avec Léo bat de l'aile. Décidée à garder son enfant, elle craint de perdre l'homme qu'elle aime.