Three new students at a super-strict girl's school must face off with a repressive school administration, the sadistic, murderous student discipline brigade and corrupt politicians over the murder/suicide of one of their friends. They're approached by a blackmailer (Tsunehiko Watase) who promises to help them exact vengeance in exchange for setting up a corrupt local politician, and aided by a independent Yakuza biker chick (Reiko Ike).

Un groupe de filles déguisées en chirurgiens tentent de voler à une autre son sang. Elle meurt en tentant de s'échapper. La police conclut à un accident. 3 nouvelles filles arrivent après cette mort. L'une d'elles connaissait la défunte...