University professor Kenzo Oshima (Hisamatsu Nobumi) is stabbed to death by someone in an alleyway in Tokyo, and Inspector Totsukawa (Takahashi Hideki) and Detective Kamei (Takada Junji) of the Metropolitan Police Department's Investigation Department's Investigative Division 1 arrive on the scene. According to the first finder, the victim died after saying "Totsukawa...". Oshima was famous as the leading authority on mitochondria, but he had never met Totsukawa... Totsukawa is puzzled, but begins to investigate, and discovers that a suspicious man has been caught on a security camera near the crime scene. Seeking a clue, Totsukawa and his colleagues interview associate professor Hayase Yumi (Kurotani Yuka) and the president of a biotechnology company, Koji Nakazono (Nakamura Shunsuke), who was assisting them in their research, to find out what happened. They find out that the man caught on the security camera is none other than their childhood friend, Akaike Shogoro (Matsuo Satoshi).

《日曜プライム》 大学教授・大島健蔵（久松信美）が都内の路地で何者かに刺殺され、警視庁捜査一課・十津川警部（高橋英樹）と亀井刑事（高田純次）は臨場する。第一発見者によると、被害者は「十津川…」と言い残して息を引き取ったという。大島は“ミトコンドリア学”の第一人者として有名な人物だったが、十津川はまったく面識がない…。戸惑いながらも捜査をはじめた十津川は、現場付近の防犯カメラに不審な男の姿が映っていたことをつかむ。 手がかりを求め、准教授・早瀬由美（黒谷友香）や研究を支援していたバイオ関連会社社長・中園宏司(中村俊介) に事情を聴いた十津川らは、驚愕の事実を知る。防犯カメラに映っていた男は、2人の幼なじみ・赤池庄五郎(松尾諭)に違いないというのだ。