Amy Rose Locane (born December 19, 1971) is an American television and film actress. She is best known for her role in John Waters' 1990 musical comedy Cry-Baby.

In September 2020, Locane began serving an eight-year sentence for a fatal DUI car crash that occurred in 2010. She had previously been sentenced to three years in prison, of which she served two and a half, and was re-sentenced due to the leniency of the original sentence.