Charles Brown Middleton (Elizabethtown, Kentucky, 3 d’octubre de 1874 - Los Angeles, Califòrnia, 22 d’abril de 1949) va ser un actor de cinema i teatre nord-americà. Durant una carrera cinematogràfica que va començar als 46 anys i va durar gairebé 30 anys, va aparèixer en prop de 200 pel·lícules, així com en nombroses obres de teatre. De vegades acreditat com a Charles B. Middleton.

Charles Brown Middleton (October 3, 1874 – April 22, 1949) was an American stage and film actor. During a film career that began at age 46 and lasted almost 30 years, he appeared in nearly 200 films as well as numerous plays. Sometimes credited as Charles B. Middleton, he is perhaps best remembered for his role as the villainous emperor Ming the Merciless in the three Flash Gordon serials made between 1936 and 1940.