Sara Gilbert is best known for her role as Darlene Conner on the ABC TV sitcom "Roseanne (1988-1997)".

She played Mitchee Arnold on the WB TV sitcom "Twins (2005-2006)" and Leslie Winkle (2007-2010, 2016) on the CBS TV sitcom "The Big Bang Theory (2007-)".

Some other TV shows she appeared on are "ABC Weekend Specials", "ABC Afterschool Specials", "Welcome to New York", "24", "Will & Grace", "Strong Medicine", "The Clinic", "Girls on the Bus", "The Class", "ER", "Private Practice", "Law & Order: Special Victims Unit", "Grey's Anatomy", "Hawthorne", "Web Therapy", "The Millers", "Bad Teacher", "Madam Secretary", "The Comeback" and "Supergirl".

She played Sudie Harrigan in the movie "Sudie and Simpson (1990)" and Sylvie Cooper in "Poison Ivy (1992)".

Some other movies she appeared in are "Calamity Jane (1984)", "Dead Beat (1994)", "Walkin' on Sunshine: The Movie (1997)", "Desert Blue (1998)", "The Big Tease (1999)", "Jack and the Beanstalk (1999)", "Light It Up (1999)", "High Fidelity (2000)", "Boys Life 3 (2000)", "Riding in Cars with Boys (2001)" and "Laws of Attraction (2004)".

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