Sasuke's long awaited battle with Itachi begins with the Uchiha brothers throwing genjutsu after genjutsu at each other. Sasuke seems to have Itachi cornered and asks him a few questions of the Uchiha massacre. Is Itachi not the only one involved in the Uchiha massacre? And does Sasuke still not possess enough hatred to defeat Itachi?

Sasuke's long awaited battle with Itachi begins with the Uchiha brothers throwing genjutsu after genjutsu at each other. Sasuke seems to have Itachi cornered and asks him a few questions of the Uchiha massacre. Is Itachi not the only one involved in the Uchiha massacre? And does Sasuke still not possess enough hatred to defeat Itachi?

Itachi reveals to Sasuke that Madara is the second culprit behind the Uchiha massacre, as well as the history of the Mangekyo Sharingan and the first two Uchiha to obtain it: Madara and his brother. One question still remains: Why did Itachi really spare Sasuke's life?

After successfully breaking out of Itachi's Tsukiyomi, Sasuke gains the upper hand on his weakened brother. With no other alternative, Itachi activates his second Mangekyo ability, Amaterasu, a black flame said to burn forever.

Sasuke thinks that he's finally killed Itachi with the help of his most powerful technique, Kirin, but Itachi still has one final trick up his sleeve. Having used both Tsukiyomi and Amaterasu, Itachi calls upon the power of his third and final Mangekyo ability, Susano'o. Itachi has turned the tide of the battle against Sasuke, but the latter receives aid from an unexpected source. The battle between the Uchiha brothers is nearing its shocking conclusion!

As Sasuke has finally fulfilled his goal in killing Itachi and avenging his clan, he collapses from exhaustion. The news of his victory reaches the Leaf ninja and Tobi, who both race towards Sasuke's location. What does Tobi plan to do with him and who will reach Sasuke first?

Seeking to gain Sasuke's trust, Madara reveals to him the origins of Konoha. Madara and the future First Hokage founded the village long ago, but a rivalry between them would one day stem a chain of events leading to THAT night, the night that Itachi Uchiha annihilated the Uchiha Clan.

After Madara finishes telling Sasuke about his past, he reveals the unfathomable truth about Itachi's massacre of the Uchiha Clan. What really happened on that night? Why did Itachi join Akatsuki? And for what reason did he really spare Sasuke's life?

The Konoha teams decide to head back home as Sasuke remembers that he saw Itachi crying after the massacre. He then states that he cannot rebuild the Uchiha clan in the same way that Itachi had envisioned. Madara, happy that he can use Sasuke for himself, assigns Taka the task of capturing the Eight-Tails while Akatsuki hunts the last two. Taka tracks down the host, Killer Bee, to the Land of Lightning and engages him in battle. Bee manages to overpower Jugo and Suigetsu before Sasuke steps up to fight him one-on-one.

Sasuke fights Killer Bee and is injured by his swords. Karin heals him, and Sasuke, Suigetsu, and Jugo then begin a combined assault on Bee until he decides to use the Eight-Tails' power. Sasuke is injured and revived again by Jugo, who regresses in age as a result. All healed, Sasuke unleashes Amaterasu on Bee, finally able to subdue him. Meanwhile, two Cloud ninja watch the fight from a cliff, and they notice the Uchiha crest on Sasuke. They rush the news to Bee's big brother, the Raikage.