Breaking the five-seal barrier set off a trap, which now has Team Guy battling amazingly accurate copies of themselves. Back at the Akatsuki hideout, Deidara and Sasori struggle to take the Nine-Tail Jinchûriki.

Teams Kakashi and Guy return home to Konoha. As Kakashi rests in the infirmary, Sakura tells Tsunade about the information Sasori gave her as a reward for defeating him. Sasori had a meeting scheduled with a spy from within Orochimaru's ranks in 10 days. 4 days have passed since Sakura received this information, and now Naruto and Sakura need to recruit a new team member to go and investigate. As Naruto searches Konoha for a willing recruit, he meets some of his old friends. Just as Choji agrees to help, Shikamaru, Choji, and Naruto are attacked by a Konoha shinobi unknown to them, Sai.

Kakashi leads Kiba, Hinata, and Shino on a mission to infiltrate Orochimaru's lair. What horrors and traps await them?

The after-effects of Guy's Daytime Tiger are felt throughout the island. Kisame is defeated, and Guy explains his technique. Yamato restrains him so Aoba can gather intel. When he's about to learn Tobi's identity, Kisame forces himself awake by biting off his own tongue. Kisame breaks free of his restraints and creates a water dome around himself. He recalls Itachi's words about learning what kind of person one is when they die. Knowing he's too weak to resist, and to prevent his enemies from gathering intel, Kisame summons sharks and allows himself to be eaten. The others are impressed by Kisame's resolution. When they open the scroll Kisame intended to deliver, it turns out to be a trap, leaving them stuck inside water prisons, while a summoned shark takes the scroll with the intel away.

The Ino-Shika-Cho trio is ordered by Shikaku to take down the reanimated Asuma. Remembering Asuma’s final words, Shikamaru and Ino are determined to stop their former teacher.

Gaara and Ohnoki manage to overcome the Second Mizukage’s mirage attack. Having taken an interest in Gaara, the Second Mizukage decides to further test the young Kage’s skills.

A reanimated boy who can control weather appears before Team Ino-Shika-Cho, Sakura, and Kiba, who are all fighting in different locations. To their surprise, the boy seems to know them.

Naruto and Killer Bee face off against the masked man originally thought to be Madara Uchiha, in addition to the reanimated Jinchuriki. Naruto is shocked when he recognizes one of the Jinchuriki.

After being saved by the target he was ordered to kill, Tenzo realizes that the man known as “Kakashi the Friend Killer” is someone who values the lives of his comrades more than anyone.