Kabuto and Yūkimaru travel to a lake, where Kabuto attempts to draw out a mysterious creature. Guren branches off from her men to find Orochimaru, who has Sasuke fight an army of Sound Ninja as training. Sasuke defeats them all, but declares that he wants to kill Itachi more than them. Naruto continues his training by summoning Gamakichi and Gamatatsu, but still doesn't understand the concept of connecting to another person's heart. Kabuto and Yūkimaru arrive at the Hot Springs Village where Naruto and Jiraiya are.

Guren is rendered unconscious and relives her past as Naruto is caught in an illusion about Sasuke. After Kakashi finds him, Teams Kakashi and Kurenai conclude the mist around them causes Genjutsu courtesy of the Three-Tails. After Guren wakes up, Yūkimaru suffers another fever and passes out. Tsunade hears of the Three-Tails and assmbles Shizune, Ino, Tenten and Lee to go and seal it before the Akatsuki do. Naruto and Sakura talk about the home that people should return to before Naruto heads off to find Yūkimaru.