Jane Lucas, overworked advice columnist for Person magazine, tries to cope with her usual hectic schedule as she advises a shy transvestite and takes a phone call from her husband informing her he's leaving her.

Jane tries to get use to being alone and to deal with the reactions from an avid press and an overwrought mother.

Laurence's interest in another woman at the hospital where he works prompts him to suggest that he and Jane have an open marriage agreement.

Jane tries to balance Laurence's demands for attention with Michael and Rob's need for her to mediate a quarrel.

Jane celebrates her birthday by taking the advice she's been giving to another woman; she leaves Laurence.