The IMF needs to get proof that Syndicate chief Sam Dexter murdered his girlfriend Vicki - Dexter is currently in prison on tax evasion and his unknown partner, The General, continues to extort millions. Jim the prosecutor produces Mimi the eyewitness who can place Dexter at the crime scene - when Dexter sends his hood Murdock, the IMF replace him by guest-agent Jack and after a faked accident implicates The General. Dexter's paid-off D.A., Reynolds, incriminates himself and ends up arrested but Dexter still refuses to cooperate. In the prison Dexter forces fellow con Barney to help him escape so he can confront the General and then return. When Dexter plans to kill Barney and the General, the IMF step in just in time.

Phelps mène une enquête parallèle à celle d'un juge d'instruction corrompu, pour prouver la culpabilité d'un patron du syndicat du crime, Sam Dexter, accusé du meurtre de sa petite amie.