Season Regulars 5

1. 

   Michael Sheen

   William Masters

2. 

   Lizzy Caplan

   Virginia Johnson

3. 

   Caitlin FitzGerald

   Libby Masters

4. 

   Annaleigh Ashford

   Betty DiMello

5. 

   Teddy Sears

   Dr. Austin Langham

Guest Stars 18

1. 

   Melanie Paxson

   Mrs. Turnsworth

2. 

   Brandon Scott

   Jessie Durkin

3. 

   Drew Rausch

   Mitch McCaffrey

4. 

   Jay Ellis

   Dr. Cyril Franklin

5. 

   Jillian Reeves

   Fannie Durkin

6. 

   Vivian Kerr

   Ingrid McCaffrey

7. Cutter Garcia

   Errol

8. Jules L. Ford

   Penelope Drake

9. Nina Daniels

   Waiting Room Nurse

10. Rebecca Kessler

    Maternity Ward Candy Striper (uncredited)

11. Benjamin Pitz

    Italian Restaurant Waiter (uncredited)

12. 

    Julianne Nicholson

    Dr. Lillian DePaul

13. 

    Greg Grunberg

    Gene Moretti

14. 

    Keke Palmer

    Coral

15. 

    Johnny Sneed

    Al

16. 

    Courtney B. Vance

    Dr. Charles Hendricks

17. 

    Jocko Sims

    Robert Franklin

18. 

    Sarah Silverman

    Helen Schiff

Crew 2