白金学院3年D组顺利毕业后，学校便倒闭了，教导主任猿渡五郎也转到了黑银学院。黑银学院有很多优秀的学生，但同样有一个恶劣的3D班。在离毕业还有3个月时又一位导师不堪折磨主动辞职，猿渡只得紧急请求教师派遣协会帮忙。结果阴差阳错派遣来的竟是他的老对头山口久美子。事已至此，两人只好硬着头皮合作。敏锐的久美子很快发现3D班的领袖矢吹隼人和休学的学生小田切龙关系微妙，她决定由此入手整顿班级，开启自己热血高校教学生涯的新篇章。

A few years passed since Yamaguchi left Shirokin Gakuen which closed after some time. Everything has been difficult for Yankumi the following years for her new students are little kids that doesn't suit her way of teaching. Change is on the horizon when a bad hair day came but with a little twist became okay. Mr. Sawatari Goro, Shirokin's vice Principal is in need of teacher in the school he is teaching. But not just ordinary teacher... he specifically need Yankumi! The school is Kurogin Gakuen. When she arrived in the school she was really happy till she knew that she is to handle another bunch of 3-D but this time meaner and more violent! As usual, she has to hide her background or else she'll lose her job. She does her best to be nice to every student but it seemed that it'll be harder for the students are worst than the word worst. How will she face them? Is it a new challenge?

実家が任侠一家の教師・ヤンクミこと山口久美子（仲間由紀恵）が、生徒たちと正面から向き合っていく姿を描く人気シリーズの第2弾。手続き上のミスにより黒銀学園へ派遣されたヤンクミは、再び問題児だらけの3年D組の担任として奮闘する。生徒役として、亀梨和也、赤西仁、速水もこみち、小池徹平、小出恵介らが登場。