星艦成員面對多項難題，除了與無所不能的外星生物 Q 再度爆發衝突，還得應付老愛追根究柢的 19 世紀作家馬克·吐溫。

Besætningen møder mange dilemmaer, lige fra en ny konfrontation med det almægtige rumvæsen Q til at håndtere en nysgerrig forfatter fra det 19. århundrede.

In season six, the crew is faced with a familiar face from the past who insists that machines cannot replace human experience. This causes conflict in Data who questions his affiliation with the Enterprise vs. joining a powerful enemy in order to feel his first emotion. Worf begins a quest to find his father as a means to finally accept his Klingon heritage and to restore honor upon his family. As the journey continues through the galaxy, Picard is kidnapped by a rebel alien command and Riker takes on the role of Captain to free Picard and restore the Enterprise. To Riker’s surprise, an old enemy returns and offers assistance with Picard’s rescue. All finishing with the Enterprise facing its most shocking surprise.

Nella sesta stagione, la troupe si confronta con un volto familiare del passato che insiste sul fatto che le macchine non possono sostituire l’esperienza umana. Ciò causa un conflitto in Data che mette in dubbio la sua affiliazione con l'Enterprise rispetto all'unirsi a un potente nemico per provare la sua prima emozione. Worf inizia una ricerca per trovare suo padre come mezzo per accettare finalmente la sua eredità Klingon e per ripristinare l'onore della sua famiglia. Mentre il viaggio continua attraverso la galassia, Picard viene rapito da un comando alieno ribelle e Riker assume il ruolo di Capitano per liberare Picard e ripristinare l'Enterprise. Con sorpresa di Riker, un vecchio nemico ritorna e offre assistenza per il salvataggio di Picard. Tutto finisce con l'Enterprise che affronta la sua sorpresa più scioccante.

Załoga musi stawić czoła wielu wyzwaniom — od kolejnej konfrontacji z wszechpotężnym Q po spotkanie z dociekliwym XIX-wiecznym pisarzem, Markiem Twainem.

La sexta temporada de Star Trek: La nueva generación comenzó el 21 de septiembre de 1992 y finalizó el 21 de junio de 1993 con un total de 26 episodios.

ลูกเรือเผชิญหน้ากับชาวควอนดารี่จำนวนมหาศาล จากการเผชิญหน้ากับเอเลี่ยนคิวที่สามารถอยู่ได้ทุกหนแห่ง ไปจนถึงการจัดการกับนักเขียนจอมอยากรู้อยากเห็นแห่งศตวรรษที่ 19 มาร์ก ทเวน