From an early age, Nia is mortified by her old-fashioned Greek family's patriotic, over-the-top ways. But, when she falls in love and marries a non-Greek teacher, Thomas Miller, her family eventually learns to accept him and Nia learns to accept her family's meddlesome ways. As Nia and Thomas return from their honeymoon to begin their new life together, they find that this new life includes her overzealous, extended family.

A Bazi nagy görög lagzi mozifilm folytatásaként a sorozat nem hagy lezáratlan szálakat: a görögországi nászútról hazatért ifjú párt nagylelkű ajándék fogadja - egy családi ház.