The unbelievable story of how the murder of Betsy Faria set off a chain of events leaving one man dead, another man implicated and a diabolical scheme exposed. Keith Morrison reports.

Nearly 10 years after Utah mother Susan Powell vanished, private journals, home videos and emails shed new light on what happened to her. Keith Morrison reports.

A double homicide in upstate New York leads detectives on a cross country investigation to piece together a case with a surprising suspect at the center. Dennis Murphy reports.

The murder of a young businessman in Old San Juan, Puerto Rico marks the start of a 15-year hunt and an international game of cat and mouse to find the killer. Natalie Morales reports.

Years after a Montana man is found dead, his son dreads what he’ll find when he opens up the box of case files, giving him insight into what really happened. Keith Morrison reports.

A woman is found murdered in her car outside of her apartment. Solving this mystery would take not just years, but also involve at least one more murder. Josh Mankiewicz reports.

A California woman eludes police after both of her husbands are found murdered nearly 20 years apart. Until fate catches up with her. Keith Morrison reports.

A Pennsylvania father has a premonition that he’ll be murdered and the case will go unsolved. Weeks later, he is found stabbed to death. But would the case go unsolved? Andrea Canning reports.

A nurse is murdered in what police say is a burglary gone wrong. The case goes cold for over two decades, until a killer is ID’d -- the last person anyone would suspect. Josh Mankiewicz reports.

A husband is shot dead in his own bed; no one else in the house was hurt, including his wife, who was sleeping beside him. Keith Morrison reports.

A California entrepreneur abruptly leaves his business to travel the world, and his family is shocked to find out he was murdered. The convicted killer speaks out. Keith Morrison reports.

A Colorado woman vanishes. No crime scene. No evidence. No body. Would a dark secret about her marriage lead to clues that solve the mystery of her disappearance? Dennis Murphy reports.

A look at the 2004 murder of pregnant California woman Laci Peterson, including rarely seen interrogation footage of her husband, Scott, who was convicted of the crime.

Identical twins find their mother's dead body in their home, located in a gated community; detectives uncover a hidden diary and clues buried in the victim's past. Keith Morrison reports.

Hiker Meredith Emerson goes missing on Georgia's Blood Mountain on New Year's Day 2008. Could her disappearance be linked to two cases with similar circumstances? Dennis Murphy reports.

After Lisa Ziegert is abducted during her evening shift at a gift shop, local detectives, state police and the FBI work relentlessly to find her and solve the case. Andrea Canning reports.

A glimpse of a sobbing woman lighting black candles is seared into a 9-year-old girl’s memory. Decades later that girl reveals what she saw, heating up a long-cold case. Keith Morrison reports.

An inside look at the case that made national headlines in December 2019, when a Texas mother was found murdered after she and her newborn daughter disappeared. Andrea Canning reports.

Family members and the lead investigators who cracked the Kelsey Berreth case speak out for the first time and take Andrea Canning inside the murder investigation

An investigation into the case of two missing Idaho children making national headlines. The trail leads Keith Morrison to Hawaii in search of their mother and her new husband.

When grad student Katie Sepich is murdered, her killer leaves behind his DNA. The Sepich family fights for both justice and to get the law on DNA collection changed. Josh Mankiewicz reports.

Karl Karlsen’s wife dies in a house fire. Then his prized horses die in a fire. And his son dies in an apparent accident. How can one man can be so unlucky? Andrea Canning reports.

A fugitive steals millions of dollars by conning numerous women and businesses over 25 years. Will law enforcement finally be able to catch him? Andrea Canning reports.

A coroner arrives at the scene of a car wreck to find a woman dead. He becomes suspicious when he notices unusual markings on her face. Was her death really an accident? Andrea Canning reports.

Three siblings’ lives change when their father is taken hostage in an orchestrated abduction. For the first time, they open up to Keith Morrison about their ordeal and its stunning conclusion.

A decades-long quest to find the truth in a young woman's mysterious death ends with a dramatic courtroom decision. The man at the center of it all tells his story to Dennis Murphy.

When Dr. Teresa Sievers is found murdered in her kitchen, detectives struggle to find any leads until an unexpected tip changes everything. Dennis Murphy reports.

A Connecticut bank executive is targeted by criminals who force him to rob his own bank. Dennis Murphy reports.

A former foster child now in the home of her case worker, goes missing with a note saying she ran away. Dennis Murphy reports.

A former FBI agent is murdered at his house, and as police dig into his past, they begin to think the key to solving the mystery might be quite close to home. Josh Mankiewicz reports.

Exclusive interviews with close family members of Lori Vallow, the Idaho mother charged with deserting her children, Tylee and JJ, who have not been seen since September. Keith Morrison reports.

The story of Rebecca Musser vs. FLDS leader and notorious FBI fugitive Warren Jeffs. Rebecca opens up to Keith Morrison about life in the church and why she decided to leave the denomination.

A tight-knit Long Island family goes to extraordinary lengths to find their missing sister. Andrea Canning reports.

When Bryan Rein, a young Montana veterinarian, is found dead at his home with a gun nearby, police quickly discover there is more to the case than meets the eye. Keith Morrison reports.

A successful businesswoman and mother of three is found shot in her office; the investigation into her death leaves a family divided. Keith Morrison reports

A mother of two who vanishes during a storm turns out to be a victim of something sinister. Dennis Murphy reports.

A man calls 911 after his estranged wife is found unconscious in the bathtub. Soon after the mysterious death, loved ones suspect what happened was no accident. Andrea Canning reports.

Lester Holt investigates the government’s response to the coronavirus pandemic and asks if better preparation could have saved lives.

Two Tulsa, Oklahoma brothers fight for more than 20 years to prove their innocence after they were each wrongfully convicted for separate murders. Craig Melvin reports.

Lori Vallow’s former best friend speaks to Keith Morrison following the discovery of the remains of Vallow’s children JJ and Tylee on husband Chad Daybell’s property.

A 59-year-old father is found dead in his home, they assume it's related to his ongoing health issues. But then, the coroner reveals he didn’t die of natural causes. Keith Morrison reports.

Andrea Canning reports on the latest developments in the case of Georgia teacher and former beauty queen Tara Grinstead who vanished nearly 15 years ago.

After a nursing student vanishes from the hospital parking lot in the middle of her shift, investigators track security footage and her cell phone to get to the truth. Keith Morrison reports.

When actress Aasha Davis and her sister Lesley move to Hollywood, things appear to be going well. But just as Aasha’s star is rising, Lesley suddenly vanishes. Josh Mankiewicz reports.

Police suspect natural causes as they investigate a man's death, until they they uncover a love triangle that turns the tragedy into a tangled mystery. Andrea Canning reports.

The latest in the case of Jennifer Dulos. In his first network interview, the lead investigator reveals new details to Dennis Murphy of what happened the day the Connecticut mother disappeared.

An explosion in a rice field in Colusa County, California kills the manager of a multi-million dollar farm. Police soon discover his death was no accident. Keith Morrison reports.

A woman falls in love with a successful doctor, but when the relationship ends things take a turn when she learns she might be the target of a murder-for-hire plot. Andrea Canning reports.

A firefighter returns home after a long shift to find a disturbingly violent scene and his wife unresponsive in their bedroom. What could have happened? Andrea Canning reports.

Multiple mysterious deaths occur inside a traveling commune, spurring a decade-long investigation that uncovers deadly and devastating secrets. Dennis Murphy reports.

An Iowa mother, home alone with her three children, is attacked. The confrontation turns fatal. But is the truth more twisted than anyone could imagine? Dennis Murphy reports.

A criminal defense attorney is found brutally murdered in her office after working late. The search for the killer takes investigators down a strange and unexpected road. Dennis Murphy reports.

Lester Holt spends two nights locked up and embedded inside the largest maximum security prison in America, the notorious Louisiana State Penitentiary, also known as Angola.

An Army veteran disappears in Southern California. Massive searches turn up nothing, but detectives do find a clue: a cryptic 911 call that helps uncover the truth. Josh Mankiewicz reports.

When police find a prominent lawyer dead and his girlfriend bound in duct tape, their investigation leads to an overwhelming list of potential suspects. Andrea Canning reports.

When a wife and mother of three disappears, police comb through her online presence to see if they can find any clues about what happened to her. Andrea Canning reports.

International celebrity Oscar Pistorius shoots and kills his girlfriend. When police arrive he says he acted in self-defense, as he believed he was firing at an intruder. Keith Morrison reports.

Days before Christmas, a high school senior is found dead in her car after visiting the mall. It would take almost 40 years for investigators to identify her killer. Dennis Murphy reports.

A suspicious house fire in Ohio sparks an investigation into a supposed suicide 24 years earlier. Josh Mankiewicz reports.

When a Colorado rancher mysteriously disappears, his friends know something isn’t right and spend years fighting for answers. Josh Mankiewicz reports.