James Burke employs a detective to illustrate how the senses pick up clues from the outside world, how the brain solves the mystery and decides what is out there. Illustrates how easy it is to fool the best detective and asks: 'What is reality?'

In order to answer the question 'When is reality?' James Burke finds himself in a Salvador Dali-like landscape and examines what motivates man, why light can never stand still and why one man's 'now' can be another man's 'then'

From the stage set of 'The Mousetrap', James Burke examines the memory and asks: does it stay the same, how does it influence everyday actions and is the script for the future already written - from memory?

Looks at the complexity of the brain handling the simplest activity. James Burke's consciousness steps out of his body for a while to demonstrate how it acts as 'Mission Controller' for his own private universe.

James Burke considers whether language is the way in which reality is shared.