传说，这个世界由人界、魔界、兽人界组成，而依据传说，三千年每三千年会出现「超神」，超神将统一这三界，创造永恒的国家。醉心于「超神传说」的兽人「天邪鬼」徘徊人间数百年，寻找「超神」，希望能看到不同于现状的美丽新世界，直到他找到在日本横滨的普通学生「南云辰夫」与其女友「伊藤明美」。然而，随著事件的发生，天邪鬼逐渐了解「超神传说」的真实面貌。

In this sequel to Urotsukidoji: Legend of the Overfiend, the unbelievable sexual violence of the Overfiend and his cohorts from Hell continues to wreak havoc on the earth. Who can stop this relentless onslaught? Urotsukidōji II: Legend of the Demon Womb was originally released as a 2 episode OVA series from December 1, 1990 to April 10, 1991 but was later re-release as a compilation film on July 21, 1991.

As the Overfiend slumbers, the mad emperor Caesar rises to power, enslaving a new race of demon beasts. Into this cruel existence is born the Lord of Chaos, the Overfiend's nemesis. As the blood-thirsty beasts capture the tyrant's daughter in a brutal coup, the Overfiend must awaken to an apocalyptic battle of the Gods.

It is the age of the Overfiend, and flesh-hungry monsters rule the Earth. Immortal half-demon Amano Jyaku travels the wasteland, witness to the rape and torture of the human race. The last hope for humanity is the demonic Lord of Chaos, the Overfiend's natural enemy. Will the world survive their final battle?

Only one episode of this was partially completed, the released version containing numerous examples of animation that is missing in-between frames. The story as such concerned the arrival of the real Chojin as he/she (a hermaphrodite) makes moves to wipe out all life on Earth. Interestingly, the setup for the show was far more heavily connected with the first two, more popular, chapters in the Urotsukidoji saga, with appearances by Nagumo and Akemi (unseen since the early episodes of Part III), and redesigned character models that more closely resembled the earlier episodes. Some of the less popular characters introduced in chapters III and IV, particularly Buju, were nowhere to be seen. Nevertheless, such strategies did little to get this final saga off the ground and the story was shelved.