An unemployed pot-smoking slacker and amateur drummer, Anthony Stoner ditches his strict parents and hits the road, eventually meeting kindred spirit Pedro de Pacas. While the drug-ingesting duo is soon arrested for possession of marijuana, Anthony and Pedro get released on a technicality, allowing them to continue their many misadventures and ultimately compete in a rock band contest, where they perform the raucous tune "Earache My Eye."

Perennially stoned Cheech and Chong tear through the city of Los Angeles, causing trouble wherever they go. After Cheech loses his job, the two pot enthusiasts head to the welfare offices where Cheech's girlfriend, Donna, works. Instead of collecting unemployment, they find themselves thrown back on the streets, searching for a way to earn new income. But when Cheech's cousin, "Red" Mendoza, arrives, things get even crazier.

Nice Dreams - it rhymes with ice creams. And that's what Cheech and Chong are selling in this thoroughly wacky comedy. The outrageous, permanently spaced-out duo sells enough of their "specially mixed" ice cream to take the cash and realize their fondest dreams: new guitars, islands in the sun and beautiful women. But, of course, not everything goes as planned. While celebrating their wealth in a new wave Chinese restaurant, Cheech meets his long-lost love Donna, and promptly escorts her to her posh penthouse. He soon learns, however, that Donna's boyfriend, an ex-con named Animal, is on his way to her boudoir. Meanwhile, Chong has unwittingly exchanged all their money for a worthless bank check - and the only way to get it back is to escape into a nearby insane asylum.

Everybody has problems these days, and Cheech and Chong are no exceptions. They're hired by Slyman and Habib to drive a limousine to Las Vegas with $5 million secretly stashed in the front seat. In order to get there, the pair sells off the car piece by piece, including the seven-figure front seat. Cheech and Chong then have a much bigger problem - Slyman and Habib are after them, swearing to kill them after the appropriate torture.

Cheech & Chong are invited to a celebrity party in Amsterdam. When they get there, however, it turns out that the guy who invited them has taken off with all the money. They are actually expecting Burt Reynolds and Dolly Parton, so our heroes get to be Mr. Burt and Mr. Dolly.

Two brothers who can feel each others' pain and pleasure mess up the French revolution.

Get Out of My Room, was a mockumentary in the style of This Is Spinal Tap, written and directed by Cheech Marin. In the film, he and Tommy Chong are shown attempting to finish a "video album" for their novelty record Get Out of My Room.