Een jonge vrouw die pas weduwe is geworden en een jonge man die pas zijn vrouw verloren heeft, proberen samen een nieuw bestaan op te bouwen in het wilde westen anno 1800.

In the 1800s frontier, Missie Davis is a bright and beautiful schoolteacher whose love for the prairie is matched only by her passion for books. When Missie encounters Grant, a handsome New England railroad executive, she feels as though she's met a hero from one of her novels.

Missie's surprise pregnancy sets her on a new course that is both thrilling and terrifying. After all the planning and dreaming, she and her husband Willie are headed west in a covered wagon, leaving behind the prairie home of Missie's parents. Now, caught between the excitement of the new adventure and the pain of not knowing when she'll see her family again, Missie copes with the challenges, and cherishes the rewards, of her new homestead.

In het niet langer helemaal Wilde Westen van eind 19e eeuw lijkt de familie LaHaye het doel van hun dromen te hebben bereikt. Ze hebben zich in hun eigen huis gevestigd als het dagelijkse leven overschaduwd wordt door de plotselinge dood van hun dochtertje. Vrouw Missie geeft haar baan als lerares op, echtgenoot Willie moet om financiële redenen de baan als sheriff op zich nemen. Dat de dochter van een boswachter met een slechte reputatie verliefd wordt op de geadopteerde zoon, maakt het leven er niet makkelijker op.

Missie three years later: being a single mother after her husband Willie was shot during a poker scuffle. She and Maddy move back in with her parents Clark and Marty. She finds a new home, and finds a new teaching position that she settles right into, but Missie has lost all faith in herself, until a chance encounter at her father's church where she adopts homeless orphan Belinda Marshall.

Centers on Missy's adopted daughter Belinda Tyler as she follows her dream. Belinda wants to be a doctor, but this time period does not look kindly on women with careers, especially one in the medical field. But Belinda is a strong-minded woman and deeply wants a career as a doctor. She manages to prove her abilities while assisting the local doctor and caring for an old woman who recently experienced a stroke. Belinda nurses her back to health and helps her regain the use of her arm again. Belinda also meets the nephew of their deceased neighbor. Drew comes to town to get his uncle's farm in shape to sell. After that he intends on returning to New York to join his father's law practice. He has no desire to stay in this small, unsophisticated town. But after meeting Belinda he has second thoughts. Belinda also feels something for Drew, but she is conflicted because she wants to be a doctor...

Belinda Simpson is now a doctor in a small Missouri town where an unknown plague is spreading fear and resentment amoung the townspeople. One local resident thinks the illness was spread from the town orphanage and wants to see it shut down. Belinda struggles to make sense of the disease and God's plan for the beleaguered town.

In this sequel, Lillian has been adopted and it's several years later. Annie, married and pregnant, visits her fellow doctor friend, Dr. Owen. Dr Owen desperately wants a baby, but seems unable to become pregnant. Lillian finds a love interest, an assistant to her adoptive dad, the latter has become quite overprotective.

Clark Davis struggles to maintain his land and support his family during a long drought. With a bank loan to repay, his wife, Ellen, takes a job in town as a seamstress, but soon becomes ill with scarlet fever. Devastated to lose his beloved wife, Clark and his young daughter Missie turn to his parents Irene and Lloyd for support. Clark must find a way to save his farm and survive Ellen's death without losing the person he loves most: his daughter.

Sinds de dood van de Barlows waakt sheriff Holden over Ellen en Cassie, die voor de familieboerderij moeten zorgen. Op de dag dat goudzoekers het dorp binnenvallen, ontmoeten de twee zussen Clark en Daniel, twee cowboys die op de boerderij komen werken. Maar nauwelijks begint Ellen Clark aardig te vinden als hij moet vertrekken, terwijl haar ex-verloofde na twee jaar afwezigheid terugkeert.

Nog rouwend om het verlies van haar man en dochter, bezoekt de weduwe Ellie King (Natalie Hall) haar broer Aaron Davis (Greg Vaughan) en zijn kinderen om Kerst te vieren. Ellie doet haar best om van de feestdagen te genieten en maakt veel nieuwe vrienden. Wanneer Aaron de stad uit gaat voor inkopen gaat Ellie ermee akkoord op zijn kinderen te letten. Maar de feestelijke sfeer wordt bedreigd wanneer Aaron vermist raakt.