When Phil and Debbie Winslow relocate from their native Kansas to the sunny climes of Orange County, their big-hearted, havoc-wreaking Great Dane gets a taste of the dog's life, California-style.

Great Dane Marmaduke epitomizes the overgrown lapdog, with an irascible streak and a penchant for mischief that is tempered with a deep sense of love and responsibility for his human family, the Winslows. The new animation is set in the world of elite dog shows, rife divas, rivalries and slapstick comedy.

The Garrisons are the "proud parents" of three adorable dachshund pups - and one overgrown Great Dane named Brutus, who nevertheless thinks of himself as a dainty dachsie. His identity crisis results in an uproarious series of household crises that reduce the Garrisons' house to shambles - and viewers to howls of laughter!

A young cat named Oliver is left alone in a kitten box, while all the other young cats have new owners. A big dog named Dodger shows him how to get food and later Oliver lives with him, his owner Fagin and Fagin's other dogs Tito, Rita, Einstein, and Francis. Fagin has one problem besides being broke he owes a nasty man named Sykes a lot of money. If he can't pay it back he's in big trouble. While Oliver runs into a little girl named Jenny who becomes his new owner which he is happy with and later Sykes sees Jenny as the key for him to get his money.

Bertram Pincus, a cranky, people-hating Manhattan dentist, develops the unwelcome ability to see dead people. Really annoying dead people. Even worse, they all want something from him, particularly Frank Herlihy, a smooth-talking ghost, who pesters him into a romantic scheme involving his widow Gwen. They are soon entangled in a hilarious predicament between the now and the hereafter!