Placed in a foster home that doesn't allow pets, 16-year-old Andi and her younger brother, Bruce, turn an abandoned hotel into a home for their dog. Soon other strays arrive, and the hotel becomes a haven for every orphaned canine in town. But the kids have to do some quick thinking to keep the cops off their tails.

Ozzy, a friendly, peaceful beagle has his idyllic life turned upside down when the Martins leave on a long and distant trip. There's only one problem: no dogs allowed! Unable to bring their beloved Ozzy along for the ride, they settle on the next best thing, a top-of-the-line canine spa called Blue Creek.

When Woodstock's fancy new nest disappears one afternoon, he turns to Snoopy for help. Adopting the guise of Sherlock Holmes (complete with cloak, deerstalker cap and bubble pipe), Snoopy and Woodstock go on the hunt for the missing nest.