Sex Change Hospital is an American six-part documentary series following trans men and women having genital reassignment surgeries. Dr. Marci Bowers performs the surgeries and calls upon her own experiences as a transgender woman to guide her patients as they go through the ultimate life changing procedure.

Miki Ogawa (Jun Shison) yearned to live the life of a lovely girl and moved to the city from the countryside because of this. She holds a job at a fashion mail order company. Miki Ogawa also has a secret. She is transgender. Although, she has a pretty woman's appearance, her gender is male. One day, Tadaomi Goto (Keita Machida) appears in front of Miki Ogawa. They graduated from the same school. Tadaomi Goto is flustered by Miki's different appearance, but they happen to live together.

Even as a child, Lee knew she was different. The feeling of being born in the wrong body grew and after hiding her transsexuality for many years, the then TV carpenter had no choice – the body had to change in order for Lee to live.