Klondike is a 17-episode half-hour American Western television series starring Ralph Taeger and James Coburn that aired on NBC. The series premiered on October 10, 1960 and ran until February 13, 1961, facing stiff competition from The Danny Thomas Show on CBS and the second half of the first-season detective series Surfside 6 starring Troy Donahue on ABC. Klondike followed Dale Robertson's Tales of Wells Fargo on the NBC schedule.

The lives of two childhood best friends, Bill and Epstein, in the late 1890s as they flock to the gold rush capital in the untamed Yukon Territory. This man-versus-nature tale places our heroes in a land full of undiscovered wealth, but ravaged by harsh conditions, unpredictable weather and desperate, dangerous characters including greedy businessmen, seductive courtesans and native tribes witnessing the destruction of their people and land by opportunistic entrepreneurs.