Conheça Yugi e seus melhores amigos Joey, Tristan e Téa. Eles compartilham um amor pelo jogo mais novo que está varrendo a nação: Monstros de Duel!

A lenda tem 5000 anos atrás, os antigos faraós egípcios costumavam jogar um jogo mágico muito parecido com os monstros de duelo. Esse jogo antigo envolveu cerimônias mágicas, que foram usadas para prever o futuro e, finalmente, decidirem o destino de alguém. Eles chamaram de jogos de sombra. Como o jogo usou tantos feitiços mágicos e criaturas ferozes, não demorou muito para que o jogo saísse do controle e ameaçasse destruir o mundo.

Nao Kanzaki, a student, was blackmailed into joining a "Liar Game" and ended up losing 100 million yen. In order to repay the debt, she enlists the help of Shin'ichi Akiyama, a genius swindler who was only recently released from jail for bankrupting one of Japan's largest scam companies.

In Big Money City, players participate in "Hero Battles" using Bankfon Gs, which allows them to rent powerful hero suits and fight battles against other players, receiving power boosts from the system's public domain feature. Kaito Goushou, a young elementary school student who is always eager to help others, ends up hastily signing a contract to rent the powerful unlisted hero suit, "Enter the Gold," from a mysteriously seedy priest named Sennen; however, he soon learns that the suit comes with a debt of 10 billion yen, and Kaito must now clear his dues by winning Hero Battles.

The anime centers around a boy named Kouta Kouka (Kouka Kouta in Japanese name order, an apparent wordplay on Coca-Cola). Kouta strives to be the world's best Bottle King at the Bottle Battles in the virtual Drink World. He comes across his Bottleman partner Colamaru and then wages battles with various rivals.

Ao longo de sete dias e seis noites, 12 concorrentes medem forças em jogos de perspicácia, estratégia e sabedoria. Quem se sagrará o grande vencedor?