קייטי פרייס, בת 17, נאלצה לבלות את כל חייה אך ורק בתחומי ביתה בשל רגישות בריאותית נדירה לאור השמש. רק כאשר יורד אור היום והלילה מתחיל, יוצאת קייטי החוצה לנגן בתחנת הרכבת הסמוכה לביתה. באחת מגיחותיה הליליות היא פוגשת בצ'רלי, בחור שהעריצה בסתר זה זמן רב. השניים מתאהבים אך קייטי חוששת מלחשוף בפניו את מצבה הבריאותי.
Auro suffers from a progeria like syndrome. Mentally he is 13 but physically he looks 5 times older. In spite of his condition, Auro is a very happy boy. He lives with his mother Vidya, who is a gynaecologist. Amol is young, progressive politician. He is a man with a mission. Auro is Amol's son. Paa is a 'rare' story about a father-son, son-father relationship.
A 22 year old man who has lived inside a crystal room because of a rare illness, meets an up and coming rock star, and the two fall in love.
Adam Pearson - who has neurofibromatosis type 1 - is on a mission to explore disability hate crime: to find out why it goes under-reported, under-recorded and under people's radar.
Young Oksana puts her newly born Denis in a baby box. Sixteen years later she steals him away from a children's home, intent on making amends for her maternal neglect, and to exploit him to earn money in a corrupt legal system.
Joan Ximénez el Petitet is a Catalan gypsy who pursues a dream. A former musician now —a percussionist, son of Ramón el Huesos who worked with the mythical singer Peret—, and affected by a rare chronic disease, he wants to accomplish the promise he made to his mother before she died: to celebrate a rumba concert on the stage of the Liceu, a great theater in Barcelona, along with a big symphony orchestra.
A man tries desperately to kill himself, but consistently fails to the amusement of the Narrator, who may or may not be behind his failure
A mother discovers that her son has a disability that causes her breast milk to intoxicate him. But the discovery comes too late to prevent the loss of neurons.