After getting dropped from an elite program, a student gets tangled in the affairs of a high school gang while trying to find her own identity.

The students of Class 3-E have a mission: kill their teacher before graduation. He has already destroyed the moon, and has promised to destroy the Earth if he can not be killed within a year. But how can this class of misfits kill a tentacled monster, capable of reaching Mach 20 speed, who may be the best teacher any of them have ever had?