Ninagawa is a powerful man in Japanese politics and with top economic connections.His granddaughter is then murdered. The suspect is Kunihide Kiyomaru. Kunihide Kiyomaru has a prior conviction for assaulting and killing a girl 8 years ago. The police could never apprehend the suspect in the prior killing.
Milo Boyd, a down-on-his-luck bounty hunter, thinks he's seeing an upswing in fortune when he gets a call to bring in his bail-jumping ex-wife, a reporter named Nicole. Milo considers the job an easy payday, but Nicole quickly escapes to chase a lead on a murder case. The former spouses play an escalating game of one-upmanship, until they suddenly find themselves on the run for their lives.
When half-breed Indian Yaqui Joe robs an Arizona bank, he is pursued by dogged lawman Lyedecker. Fleeing to Mexico, Joe is imprisoned by General Verdugo, who is waging a war against the Yaqui Indians. When Lyedecker attempts to intervene, he is thrown into prison as well. Working together, the two escape and take refuge in the hills, where Lyedecker meets beautiful Yaqui freedom fighter Sarita and begins to question his allegiances.
The signs indicate current bounty prices: $50 for a fox, $75 for a bear, only 2 cents for a rabbit. Bugs is insulted.