A team of specialized Autobots not quite ready for prime-time battles against the Decepticons is given a vital mission by Optimus Prime. The goal for the Bots is to learn about mankind and how to help others to find out what it really means to be a hero.

Years after the events of Predacons Rising, Bumblebee is summoned back to Earth to battle several of Cybertron's most wanted Decepticons that escaped from a crashed prison ship and assembles a team of young Autobots that includes Sideswipe (a rebel "bad boy bot"), Strongarm (an Elite Guard cadet), Grimlock (a bombastic Dinobot), and Fixit (a hyperactive Mini-Con with faulty wiring).

Roll out with Optimus Prime, Bumblebee, Arcee, Ratchet, Bulkhead, and the rest of the heroic Autobots as they battle the evil Decepticons. Now that big bad Megatron has returned with a mysterious and dangerous element, Team Prime must prepare for an epic battle.

Five students of the Rescue Bots Training Academy from Cybertron—Hot Shot, Whirl, Medix, Hoist and Wedge—learn to respond to emergency situations and become heroes.