Days before Valentine's day and their wedding, Cindy Hunter, editor-in-chief of a tabloid and Damon Tuckland, a successful therapist encounter a strange plant that magically puts Cindy's mind in Damon's body and vice versa. Now the couple really finds out how the other half lives. In a series of comic mishaps at work, with relatives and at home, Cindy and Damon must become better people and figure out a way to reverse the "awkward" situation before their wedding or face a lifetime as each other. It's the ultimate body-swapping comedy with a heart that gives a brand-new meaning to the term "The Opposite Sex".

Likus kelioms dienoms iki Valentino dienos ir jų vestuvių, vyriausioji bulvarinio laikraščio redaktorė Cindy Hunter ir sėkmingas terapeutas Damonas Tucklandas susiduria su keistu augalu, kuris stebuklingai perkelia Sindy mintis į Deimono kūną ir atvirkščiai. Dabar pora iš tikrųjų sužino, kaip gyvena antroji pusė.