Pemeran 19

1. 

   Shameik Moore

   Miles Morales (voice)

2. 

   Hailee Steinfeld

   Gwen Stacy (voice)

3. 

   Brian Tyree Henry

   Jeff Morales (voice)

4. 

   Luna Lauren Velez

   Rio Morales (voice)

5. 

   Oscar Isaac

   Miguel O'Hara (voice)

6. 

   Jake Johnson

   Peter B. Parker (voice)

7. 

   Jason Schwartzman

   Spot (voice)

8. 

   Issa Rae

   Jessica Drew (voice)

9. 

   Daniel Kaluuya

   Hobie Brown (voice)

10. 

    Nicolas Cage

    Spider-Man Noir (voice)

11. 

    John Mulaney

    Spider-Ham (voice)

12. 

    Kimiko Glenn

    Peni Parker (voice)

13. 

    Amandla Stenberg

    Margo Kess (voice)

14. 

    Karan Soni

    Pavitr Prabhakar (voice)

15. 

    Mahershala Ali

    Uncle Aaron (voice)

16. 

    Jharrel Jerome

    Miles G. Morales (voice)

17. 

    Greta Lee

    LYLA (voice)

18. 

    Andy Samberg

    Ben Reilly (voice)

19. 

    Shea Whigham

    George Stacy (voice)

Kru 27