塞雷娜·威廉姆斯（Serena Williams），1981年9月26日生于美国密歇根州塞基诺市，美国女子职业网球运动员。

塞雷娜·威廉姆斯是同时代女网天后维纳斯·威廉姆斯的亲妹妹，所以通常称呼她为“小威廉姆斯”，简称“小威”。小威是典型的美国黑人选手，恐怖的力量、爆发力以及雄厚的比赛经验让小威几乎统治了女子网坛，她是力量、技术、心态和智慧完美结合的球员。

Serena Williams, is one of the top female tennis player in the world, has always maintained a level of interest. She earned her first grand slam singles title at the U.S. Open back in 1999, and made a string of four straight grand slam singles title wins - the 2002 French, Wimbledon, and U.S. Open titles, and the 2003 Australian Open title, all achieved by defeating her older sister, Venus. A knee injury in 2003 forced her to sit out 8 months of tennis competition. She reached the Wimbledon final in 2004, but has not won a major title since the summer of 2003. As of late, Serena has taken a stab at acting, appearing in guest roles on both Simpsons (1989) and My Wife and Kids (2001).