Lili Anne Taylor (born February 20, 1967) is an American actress. She came to prominence with supporting parts in the films Mystic Pizza (1988) and Say Anything... (1989) before establishing herself as one of the key figures of 1990s independent cinema through starring roles in Bright Angel (1990), Dogfight (1991), Household Saints, Short Cuts (both 1993), The Addiction (1995), I Shot Andy Warhol,  Girls Town (both 1996), Pecker (1998), and A Slipping-Down Life (1999). Taylor is the recipient of four Independent Spirit nominations, winning once in the category of Best Supporting Female. Her other accolades include one Golden Globe Award and three Primetime Emmy Award nominations.

Alongside her work on smaller-scale projects, Taylor has encountered mainstream success with parts in films such as Born on the Fourth of July(1989), Rudy (1993), Ransom (1996), The Haunting (1999), High Fidelity (2000), Brooklyn's Finest, Public Enemies (both 2009), The Conjuring (2013), and Maze Runner: The Scorch Trials (2015). Other credits include The Notorious Bettie Page (2005), Starting Out in the Evening (2007), The Promotion (2008), Being Flynn (2012), To the Bone, Leatherface (both 2017), Eli (2019), and Paper Spiders (2020).

Outside film, Taylor has appeared in television series such as Almost Human (2013–2014), Hemlock Grove (2013–2014), and Outer Range (2022-2024). For her portrayal of Anne Blaine on three seasons of American Crime (2015–2017), she was nominated for the Primetime Emmy for Outstanding Lead Actress. She received two Emmy nominations for her roles as Marty Glenn on The X-Files (1998) and Lisa Kimmel on Six Feet Under (2002–2005). Taylor's stage credits include Broadway productions of Anton Chekhov's Three Sisters (1997) and Scott McPherson's Marvin's Room (2017). She is married to playwright Nick Flynn, with whom she has a daughter.