Stała obsada sezonu 6

1. 

   Hugh Laurie

   Gregory House

2. 

   Lisa Edelstein

   Lisa Cuddy

3. 

   Robert Sean Leonard

   James Wilson

4. 

   Omar Epps

   Eric Foreman

5. 

   Jennifer Morrison

   Allison Cameron

6. 

   Jesse Spencer

   Robert Chase

Goście specjalni 15

1. 

   Leslie Hope

   Victoria Madsen

2. 

   Larry Clarke

   Officer Gilmar

3. 

   Smith Cho

   Julia

4. 

   Ogy Durham

   Chris Dewey

5. Leslie Karpman

   Jodi

6. 

   Charles C. Stevenson Jr.

   Walter

7. 

   Suzanne Ford

   Mrs. Whitney

8. Brandon Brocato

   Phil

9. Graciella Evelina Martinez

   Tall Girl

10. 

    Patty Onagan

    Girlfriend

11. Farrah Skyler Greye

    Nurse

12. 

    Bonnie Perlman

    Mom

13. 

    Troy Robinson

    Cop

14. Paul Sklar

    Cop

15. Kevin Moon

    EMT

Ekipa 5