시즌 정규 출연진 6

1. 

   Hugh Laurie

   Gregory House

2. 

   Lisa Edelstein

   Lisa Cuddy

3. 

   Robert Sean Leonard

   James Wilson

4. 

   Omar Epps

   Eric Foreman

5. 

   Jennifer Morrison

   Allison Cameron

6. 

   Jesse Spencer

   Robert Chase

특별출연 15

1. 

   David Morse

   Michael Tritter

2. 

   Pruitt Taylor Vince

   George

3. 

   Kadeem Hardison

   Lawyer Howard Gemeiner

4. Ryan Thomas Brockington

   Rookie

5. 

   Mary Elizabeth Ellis

   Sophie

6. 

   Cooper Thornton

   John

7. 

   Damien Dante Wayans

   Haller

8. Denver Dowridge

   Garcia

9. 

   Richie Chance

   Reilly

10. 

    Bruno Amato

    Lt. Smith

11. 

    Jim Vickers

    Folman

12. Michael James Faradie

    Paramedic

13. Alan Frazier

    Vagrant

14. Bobbin Bergstrom

    Nurse

15. 

    Stephanie Venditto

    Nurse Brenda Previn

제작진 9