Artistes récurrents de la saison 4

1. 

   Jonny Lee Miller

   Sherlock Holmes

2. 

   Lucy Liu

   Joan Watson

3. 

   Jon Michael Hill

   Marcus Bell

4. 

   Aidan Quinn

   Thomas Gregson

Vedettes invitées 13

1. 

   Erik Jensen

   Isaac Proctor

2. 

   John Bedford Lloyd

   Lieutenant

3. 

   Lucas Caleb Rooney

   Duane Proctor

4. 

   Christopher McCann

   Dr. Del Santo

5. 

   Dominic Fumusa

   Jordan Conroy

6. 

   Michael Aronov

   Andrej Bacera

7. 

   Austin Lysy

   Chad Lerberg

8. 

   Arnold Vosloo

   Christos Theophilus

9. 

   Justine Cotsonas

   Jovana Bacera

10. 

    Karen Ludwig

    Melanie Waters

11. Michael Iannucci

    Medical Examiner

12. 

    Natalie Dormer

    Jamie Moriarty

13. 

    DeLance Minefee

    Fine Diner (uncredited)

Équipe technique 23