Artistes récurrents de la saison 4

1. 

   Jonny Lee Miller

   Sherlock Holmes

2. 

   Lucy Liu

   Joan Watson

3. 

   Jon Michael Hill

   Marcus Bell

4. 

   Aidan Quinn

   Thomas Gregson

Vedettes invitées 15

1. 

   Sutton Foster

   Tara Parker

2. 

   Patch Darragh

   Griffin Parker

3. 

   Arian Moayed

   Yusuf Al Shamsi

4. Martin LaPlatney

   Darryl Jarvis

5. 

   Paul Urcioli

   Jonah Chait

6. 

   Tony Crane

   Everett Keck

7. Danny Boushebel

   Rashid Musharakh

8. 

   Kevin O'Rourke

   Deputy Commissioner Pat

9. 

   Lisa Emery

   Mrs. Barnes

10. 

    Dorothy Lyman

    Belinda

11. David Michael Garry

    Hugo

12. 

    Adam Sietz

    Rick

13. 

    Frank Vlastnik

    Handwriting Expert

14. Chris Kepford

    CSU Tech

15. 

    Tyler Weaks

    Officer Hayes

Équipe technique 6